Elevated vitamin A intake and serum retinol in preadolescent children with cystic fibrosis 1.
Elevated vitamin A intake and serum retinol in preadolescent children with cystic fibrosis 1.
Am J Clin Nutr. 2006 Jul;84(1):174-182
Authors: Graham-Maar RC, Schall JI, Stettler N, Zemel BS, Stallings VA
BACKGROUND: Persons with cystic fibrosis (CF) and pancreatic insufficiency (PI) are at risk of vitamin A deficiency because of steatorrhea, despite pancreatic enzyme replacement. Long-standing vitamin A supplementation may increase the risk of vitamin A toxicity. OBJECTIVE: The aim was to describe the vitamin A intake and serum retinol concentrations of preadolescent children with CF, PI, and mild-to-moderate pulmonary disease, who were cared for under current practice recommendations. DESIGN: This cross-sectional study evaluated children aged 8.0-11.9 y with CF and PI from 13 US CF centers. Dietary and supplemental vitamin A intakes were compared with the Dietary Reference Intakes (DRIs) for healthy children, CF recommendations, and data from the National Health and Nutrition Examination Survey (NHANES), 1999-2000. Serum retinol concentrations were compared with NHANES data. RESULTS: The 73 subjects with CF had a dietary vitamin A intake of 816 +/- 336 mug retinol activity equivalents (165 +/- 69% of the recommended dietary allowance), which was similar to the NHANES value. The supplement intake provided 2234 +/- 1574 mug retinol activity equivalents/d and exceeded recommendations in 21% of the subjects with CF. Total preformed retinol intake exceeded the DRI tolerable upper intake level in 78% of the subjects with CF. The serum retinol concentration was 52 +/- 13 mug/dL (range: 26-98 mug/dL), which was significantly higher than the NHANES value (37 +/- 10 mug/dL; range: 17-63 mug/dL; P
PMID: 16825693 [PubMed - as supplied by publisher]
]]>
Related posts:
- Intake of vitamin D by Finnish children aged 3 months to 3 years in relation to sociodemographic factors.
- Definition of metabolic syndrome in preadolescent girls.
- Dietary intake in immigrant Arabian pregnant women.
- The positive impact of red palm oil in school meals on vitamin A status: study in Burkina Faso.
- Overweight, obesity and elevated blood pressure in children and adolescents.